Kuwedzera kuvimbika kwechirwere chekuongorora

Kunonoka kuongororwa kwezvirwere zvinotapuriranwa kuisa huwandu hwevanhu vari panjodzi munyika yedu yepasi rose, kunyanya nehutachiona hwezoonotic hunotapurirwa pakati pemhuka nevanhu. Inofungidzirwa kuti makumi manomwe neshanu muzana emakumi matatu ehutachiona hwevanhu huchangobva kuwanikwa akanyorwa mumakore makumi matatu apfuura muna 2008 ndeemhuka, sekureva kweWHO yakaburitswa muna 2021.

"Chikwata chedu chakazvipira kukunda matambudziko ekugadzira dhizaini yekushandira iyo yekuongorora kudiwa kwePOCT kumhanya uye kuwanikwa mune ese IVD (in-vitro) uye isiri-IVD, "anodaro Lianyi Xie, uyo akatanga Hangzhou Bigfish Bio-tech Co., Ltd, muna 2017. "Nyedzo yedu yekuongorora (POCT) yakagadzirirwa kushanda nokukurumidza mumamiriro ekugadzirisa zviwanikwa, panguva yekudya. nokuda kwezvirwere zvakasiyana-siyana.”

Bigfish's POCTs yakagadzirirwa kuchengetedza kuchengetedzwa kwechikafu, pamwe nehutano hwezvipfuyo nemhuka dzinofambidzana, kunyanya tichitarisa kuwedzera kweChina kwevaridzi vezvipfuyo.

Kurumidza POCT dhizaini mvumo, Xie akatsanangura, inofanirwa kutsika chiyero pakati pehunyanzvi uye kutarisa kune yechinyakare uye yakavimbika amplification tekinoroji, yakavakirwa papolymerase chain reaction (PCR), kuona maminetsi ehuwandu hwenyucleic acids kubva kune yakaoma midhiya.

Funga nezvekubuda kweAfrica swine fever (ASF) kuChina, kumusha kune musika mukuru wenguruve wepasi rose wekugadzira uye kudyiwa kwemusika. Muna 2019, ASF yakakonzera kufa kwenguruve dzinopfuura mamirioni makumi mana nematatu, uye yakatenderedza madhora US 111 bhiriyoni mukurasikirwa. Kukurumidzisa magadzirirwo ePOCT kunovimba nekubatana kwepedyo nemasangano ezvidzidzo uye ehurumende, pamwe nemhinduro kubva kuvashandisi, sevanopfuya nguruve veChina.

"Kurongeka uye kunzwisiswa maererano nemagadzirirwo emurabhoritari, kunyangwe mumapurazi madiki ari kure, akakosha kune makiti edu, ayo anogadzirwa kuti akwanise uye ari nyore kushandisa pane chero mombe," anotsanangura Xie.

Basa reBigfish pakudzivirira uye kupedza chirwere chenyika yose rinosvikawo kubrucellosis, inosara iri chirwere chezoonotic pasi rose, pamwe nezvirwere mumhuka dzinofambidzana.

Bigfish yakafambisa nekukurumidza POCT munzvimbo dzinosvika zviuru zvina zvezvipatara muChina. Shuilin Zhu, sachigaro weZhejiang Small Animal Protection Association, akawedzera kuti tekinoroji yekambani yemhuka.

kuchengetwa kwezvipfuyo kwete kungowedzera kugona kwekudzivirira nekudzora, asiwo zvakanyanya kunatsiridza hutano hwemhuka.

Kugonesa dhizaini dhizaini pasina mutengo wakakura kune vashandisi ndechimwe chinhu chakakosha mukugadzira uye kugadzira kune yavo genetic test. Yavo molecular diagnostic assay GeNext haina kukura kupfuura bhodhoro remvura, uye inorema makirogiramu maviri. Iyo inoratidzira mesofluidic uye microfluidic machipi ayo anogadzirisa nhanho dzinorema kubva kunucleic acid kubviswa, kukwidziridzwa kwemajini kune chaiyo-nguva yekurodha data uye kuongorora.

Yakanyatsovharirwa kudzivirira kusvibiswa kweaerosol, iyo GeNext 2.0 ikozvino mukugadzirwa kwehuwandu inogona kugonesa sampuli yekuwedzera kubva pa1 kusvika 16 paround, kutevedzana kwakanangwa kwakawedzera kubva pa5 kusvika 25 pakumhanya, pasina imwe nguva kana mutengo.

"Madhizaini edu eGeNext 3.0 achawedzera kuderedza nguva, kusimudzira nesilicon-based chips, uye nekubatanidza matekinoroji ekutevedzana senge nanopore sequencing yehupamhi hwekiriniki mamiriro ekuongororwa kwekuzvarwa uye kuongororwa kwegomarara," anodaro Xie. "Magadzirirwo edu ePOCT rimwe zuva anogona kushandiswa nemunhu chero kupi pasina kufunga nezvemutengo."