Yakawanda sei iyo Omicron's Toxicity yakaramba? Multiple chaiyo-nyika zvidzidzo zvinoratidzira

"Hutsva hweOmicron iri pedyo neiyo yefuma yemwaka" uye "OMIMIMILON yakanyanya kuderera pathogenic kupfuura Delta". ...... Munguva pfupi yapfuura, nhau dzakawanda nezvewanano rekorona nyowani mutant Strain Omikroni yave ichipararira paInternet.

Chokwadi, kubvira pakabuda kweOmicron Mutant Strain munaNovember 2026 uye nekutsvagisa kwenyika yepasirese, kutsvagisa uye kukurukurirana kuri kuitika uye kutapurirana kwakapfuurira kusina kuenderera mberi. Ndeipi iripo rirutulence profile yeOmicron? Tsva Tsva Tsvagurudzo nezvei nezvazvo?

Zvidzidzo Zvakasiyana-siyana zveLaborators: Omikroni isinganyanye hutachiona
Muchokwadi, kutanga kwaJanuary 2022, chidzidzo kubva kuYunivhesiti yeHong Kong li Ka shing Faculty of Disming (B.1.1.529) inogona kunge iri pasi pePathogenic neyekutanga madhimoni.
Izvo zvakawanikwa kuti Omicron Mutant Strain yaive isingashandise transmembrane Serine Revhitiko Panguva imwecheteyo, vaongorori vakaona kuti kudzokorora kweOmicroni kwakaderedzwa zvakanyanya mumitsara yemunhu calu3 uye cacom2.

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MuK18-Hace2 Mouse Model, Ommication Omplication muzvikamu zvepasi uye zvakaderera zvekupenga zvakakonzera kushoma, uye kushungurudzika kwehuremu hwakaderera uye kushamwaridzana kwekutanga uye alpha, beta uye delta mutants.
Naizvozvo, vatsvagiri vakagumisa kuti kudzokorora kweOmicron uye pathogenicity kwakaderedzwa mumakonzo.

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Pana 16 Chivabvu 2022, zvisikwa zvakaburitsa pepa neYoshihiro Kawaoka, inotungamira virologist kubva kuTokyo uye ichisimbisa kekutanga mumhando yemhuka iyo Omicron Ba.Zviratidzo zvisingaite kupfuura iyo yapfuura yekutanga kunetseka.

Vatsvagiri vakasarudzwa vanogara muBA.2 MAHARA VAKAWANDA BACE BACE NEMAHARA.

Iyi yegoridhe yakajairika mhedzisiro inosimbisa kuti Omikroni isinganyanye kutyisa kupfuura iyo yekutanga mhando yemusango. Mukupesana, pakanga pasina musiyano wakakosha muutambo hwezvinhu mumapapu uye mhino dzemhando yemhuka dzinotevera ba.2 uye ba.1 hutachiona.

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PCR VIRIAL Loads learts airatidza kuti vese ba.0.1 neBE.

Zvakafanana nemhedzisiro yemakonzo, iyo vira yechiitiko yakaonekwa mumhino nemapapu.0

Yakanga yakawedzera kuwana kuti matare epakutanga, ba.2 uye ba.1, aishayikwa-kusarerekera kwesera anotevera

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Real-World Dathiti: Omikroni isingakwanisi kukonzera kurwara kwakakomba

Zvikamu zvinoverengeka zvezvidzidzo zvepamusoro zvakarondedzera hutachiona hweOmicron mumhando dzematare, asi ndizvo zvimwe chete munyika chaiyo?

Pa7 June 2022, uyo akaburitsa mushumo achiongorora mutsauko mukuomarara kwevanhu vakatapukirwa panguva yeOmicron (B.1.1.529) denda rinofananidzirwa nedenda revaDelta.

Mushumo unosanganisira 16,749 New Coronary Inpatients kubva kumatunhu ese eSouth Africa, kusanganisira 16,749 kubva kuDelta Epidemic (2021/8/0/3) uye 17,693 kubva kuEmicron Apidemic (2021/11/11 kusvika 2022/2/15). Varwere vakarongedzwawo seyakanyanya, yakakomba uye isina-yakakomba.

Kutsoropodza: ​​Kuwana mhepo inosvikirwa, kana oksijeni uye yakakwira-inoyerera transnasal oksijeni, kana yekuwedzera yekuwedzera membrane oxygenation (ecmo), kana kubvumidzwa kune icu panguva yekudyara muchipatara.
-Zvese (Zvakasimba): Yakagamuchirwa okisijeni panguva yekupararairira
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Iyo data yakaratidza kuti mudunhu reDelta, 49.2% vaive vakakomba, 7.7% vaive vakanyanya uye 28% veboka revarwere vakatapudza Zvakare, urefu hwenyika hwekugara hwaive mazuva manomwe muboka reDelta vachienzaniswa nemazuva matanhatu muboka reOmicron.

Uyezve, mushumo wacho wakaongorora kuti zvinhu zvezera, zvechikadzi, zvinongedzo zvekurwara zvakakomba (b.1.100)

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Kune iyo yakasarudzika nzvimbo dzeOmicron, zvimwe zvidzidzo zvakaongororawo hutachiona hwavo zvakadzama.

Chidzidzo cheCohort Kubva kuNew England chakaongororwa 20770 zviitiko zveOmicon B.1.1.529 nyaya dzeOmiclon ba.7% yeDelta, 0.1.5 Mushure mekugadzirisa zvinhu zvinosvibisa, ongororo yacho yakagumisa kuti njodzi yerufu yaive yakaderera zvakanyanya kune ba.2 uchienzaniswa neese delta uye B.1.1.529.

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Chimwezve chidzidzo kubva kuSouth Africa chakaongorora njodzi yekuparadza muchipatara uye njodzi yemhedzisiro yakaoma yeDelta, ba.1, ba.2 uye ba.4 / BA.5. Mhedzisiro yacho yakaratidza kuti yevarwere vane 98,710 ichangotapukirwa inosanganiswa mukuongorora, 3825 (3.9%) vakabvumirwa muchipatara, vaani 1276 (33.4%) vakagadzira chirwere chakakura.

Pakati pevaya vakatapukirwa nezvimwe zvisizvo kuzvitaura, 57.7% yevarwere veDelta vakave nehosha yakaipa Ongororo yeltivariate yakaratidza kuti mukana wekukudziridza chirwere chakakomba pakati peavo vane hutachiona> ba.1> BA.
Kuderedzwa hutachiona, asi kusvinura zvinodiwa

Zvidzidzo zveRabhurosi uye data chaiyo kubva kunyika dzinoverengeka dzakaratidza kuti Omomrron uye zviisiki zvayo hazvina hutachiona uye zvishoma kukonzera chirwere chakakomba pane kutambudzika kwakanyanya uye kumwe kutambudzika kwekutanga.

Nekudaro, chinyorwa chekuverenga muNyaya yaJanuary 2025 yeLancet, asi Usaite Zvepanyama ' (Kunyange zvakadaro, mune ino dzinowanzove ruzhinji rweSouth Africa, 21% yevarwere vechipatara vane hutachiona-coMICTION vakapa uye vanokonzeresa kupfuma uye vakaderera.

Pakupera kwambotaurwa, kuti timu yakacherekedza kuti kunyangwe hosha yadarika yechipatara yechipatara (b.1.159) Varwere vepamusoro vakaramba vachiita kuti morrucity vakweguru, vakafa muhuwandu hwevakuru, . VOCS) inoramba ichiparira kuti ive yakakura morbidity uye kufa.)

Yepamberi yedata kubva kuOmicrered paChidimbu Cheshanu chePanmic muHong Kong

Mukupesana, 2% chete zera zera rinopfuura makore makumi matanhatu emakore hadzina kusarudzika, iro rakanyatsoenderana nehuwandu hwekufa kwehuwandu hwe0.07 yeiyo korona yeiyo korona yeCrown.

Kune rimwe divi, apo kazhinji zvinokonzerwa newcastle kuti nyowani inogona kuve chirwere chemwaka, mune ramangwana mune ramangwana, kune nyanzvi dzedzidzo dzinotora maonero akasiyana.

Vatatu masayendisiti kubva kuYunivhesiti yeOxford uye European Union Joint nzvimbo yekutarisa yeOmicroni inogona kungoita basa reOmicron

Kusiyana nemhosva yekusvikirwa uye kutapurirana, izvo zvinoiswa pasi pekusimudzira kumanikidzwa, hutsva hunowanzova 'ne-chigadzirwa' chekushanduka-shanduka. Virmes vanobva vawedzera kuwedzera kugona kwavo kupararira, uye izvi zvinogona zvakare kukonzera kuwedzera hutachiona. Semuenzaniso, nekuwedzera mutoro wehutachiona kuti ufambise kutapurirana, zvichiri kuchiri kuita kuti chirwere chakanyanya.

Kwete izvozvo chete, asi hutachiona huchakukonesawo mukupararira kwehutachiona kana zviratidzo zvehutachiona zvinonyanya kutapudza hutachiona - sekutumidza kuti vashoma, vane nguva yakawanda, iyo ine nguva yakawanda yekupararira isati yanganisa mhedzisiro yakakomba.

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Mumamiriro ezvinhu akadaro, zvinogona kuve zvakaoma kufanotaura maitiro eiyo korona nyowani mutanza, asi nhau dzakanaka dzekuratidzira huwandu hwehutachiona hwemahara
Kubvuma: Ichi chinyorwa chakanyatsoongororwa nePanpan Zhou, PHD, tsinghua University chikoro chekurapa uye postdoctoral shamwari, runyota runyama Institute, USA
Omikron kuzvidzora antigen reagent kumba