Iko kushanduka kweiyo yekudyira yeTymal: Shanduko muDNA S60plation

Theermal cyclersvava chishandiso chakakosha kune vanotsvaga uye masayendisiti vari muminda yemanyorerwo ezvinyorwa uye genetics. Ichi chishandiso chakavhenekera chakandichinja iyo DNA yekuwedzera maitiro, ichiita kuti ichikurumidza, inoshanda zvakanyanya, uye yakanyatsojeka kupfuura zvakamboitika. Mune ino blog, isu tichaongorora kuvandudzwa kwemitambo yekufamba-famba uye kukanganisa kwavo pamunda wemanyorerwo ebiaology.

Pfungwa yekudyara cycling, iyo inosanganisira kudzora kudziya uye kutonhora musanganiswa wekuita, ndiyo nheyo yePolymerase Chain yekuita (PCR). PCR ndiyo nzira inowedzera imwe chete kana mashoma emakopi ekutambanudza kweDNA nezvimwe zviyero zvehukuru, kubereka zviuru kumamiriyoni emakopi ezvikamu zveDND. Iko kuvandudzwa kwemitambo yedhorobha kwakaita basa rinokosha mukushandisa kwakapararira uye kuvandudza kwePR two.

Kutama kwekutanga kweThelmal kwaive bulky uye kudikanwa bhuku rekushisa tembiricha uye kuongorora kazhinji. Nekudaro, sekudyidzana kwehunyanzvi Uku kuvandudzwa kwacho kwakawedzera zvakanyanya kumhanya uye kushanda kweDNA FNAYS

Imwe yekiyi inokona muThe thermal Cyler Tekinoroji yaive yekutanga kweGradient PCR, iyo inobvumira kupisa kwakawanda kwekuwedzera kwekutsamwa kuongororwa panguva imwe chete pakuedza kumwe chete. Iyi ficha yakaratidza kuve inobatsira kwazvo mukudzora PRR mamiriro eiyo chaiwo template, inochengetedza vanoongorora nguva uye zviwanikwa.

Uye zvakare, kubatanidzwa kweiyo chaiyo-nguva pl cr kugona muzvimisikidzwa zvekutenderera kwakawedzera kuwedzera kushandiswa kwavo. Chaizvoizvo-nguva PCR, anozivikanwa zvakare seVeritative pcr, monitors DNA munguva chaiyo, ichipa yakakosha ruzivo mune yekutanga huwandu hwenzvimbo yekutarisirwa DNA. Izvi zvakachinjika nzvimbo dzakadai seGene Kutaura kuongorora, genotyping, uye pathogen kuonwa.

Iyo miniaturization yeTermal cyleckrs yave yakakosha maitiro mumakore apfuura, inotungamirirwa nekudikanwa kwekutarisa uye kushanda zvakanaka. Aya maCompact, anotakurika Thermar kutenderera akawana zvikumbiro mumunda kutsvagurudza, zvine chekuita neDziviriro, uye mune zvigadziriso-zvigadzikiso zvinowanikwa zvisikwa zvekutambisa zviripo zvinogona kunge zvichishayiwa.

Kutarisira kumberi, ramangwana retheermal cyclersuchaona zvimwe zvigadzirwa. Pfupi tekinoroji dzakadai seDhijitari PCR uye isothermal mafambiro ari kutyora miganhu yeDNA

Mukupfupikisa, kukura kweiyo denderedzwa comecls kwakanganisa zvakanyanya pamunda wemasocial biology, kutyaira kufambira mberi mukutsvaga, diagnostics, uye biotechnology. Kubva pane zvekutanga zvinyorwa zvekudziya zvibodzwa zvemazuva ano Sezvo tekinoroji inoramba ichisimudzira, basa revapambi zvekutenderera mukuumba ramangwana remanyorero ezvinyorwa zvine chokwadi kuti rirambe rakakosha.