Iko kuwanda uye kukosha kwemapuranga akadzika-mune rabarator yemazuva ano

Munyika inogara ichishanduka yesainzi yekutsvaga kwesainzi uye yekuedza, zvishandiso nemidziyo inoshandiswa mumatareji vanoita basa rakakosha mukubudirira kwemapurojekiti akasiyana siyana. Chimwe chishandiso chakakosha chakadai ndiro yakadzika-yakadzika. Aya mahwendefa akakosha ave kuita-minda mumarabhoritari mazhinji, kunyanya mumapoka akadai minda yeiyo molecular biology, biochemistry, uye kuwanikwa kwezvinodhaka. Mune ino blog, isu tichaongorora zvinoenderana nekuchinja uye kukosha kwemasango akadzika, mafaro avo, uye nezvakanaka zvavanounza vatsvagiri.

Ndeipi tambo yakadzika kwazvo?

A Yakadzika PlateIcho microplate ine matsime ematsime, imwe neimwe yakagadzirirwa kubata huwandu hombe dzemvura kupfuura iyo microplate. Mahwendefa akadzika anowanzoitwa emhando yepamusoro epurasitiki uye anouya akasiyana siyana emagetsi ane masimba ehuremu kubva ku1 ml kusvika ku10 ml kana kupfuura. Aya mahwendefa akagadzirirwa kubvumira kuti uwedzere kuganhurira, kusanganisa, uye kuongororwa, kuita chishandiso chakakosha mumarabhoritari mazhinji emarabhoritari.

Kushandiswa kweiyo Yakadzika Plate

Mahwendefa akadzika ane huwandu hwakawanda hwekushandisa, kusanganisira asi husina kugumira ku:

1. Sampule kuchengetedza: Vatsvagiri vanowanzo shandisa zvakadzama mahwendefa ekuchengetedza kwenguva refu kwemasampulogical samples samea, rna, mapuroteni, uye tsika tsika. Iyo yakakura kwazvo zvakanaka, iyo yakachengeteka iyo muenzaniso inogona kuchengetwa pasina njodzi yekuveza kana kusvibiswa.
2. Yakakwira-incoput kuongorora. Ivo vanogonesa vaongorori kuyedza zviuru zvezvibvumirano zvakafanana, nekumhanya zvakanyanya kuzivikanwa kwevanogona kuvhomedzerwa zvinodhaka.
3. Pcr uye qpcr. Ivo vakagadzirirwa kugonesa kubhururuka kwemasipi yekudyara uye kuderedza njodzi yekuyambuka-kusvibiswa pakati samples.
4. Protein crystallization. Makomba akakura anopa zvakakwana nzvimbo yekukura kwekristaro, iyo yakakosha kune X-ray crystallography fundo.
5. Tsika Tsika: Mahwendefa akadzika anoshandiswawo kumasero ezvinyorwa munzvimbo yakadzorwa. Dhizaini yavo inobvumira akawanda mitezo mitezo kuti ibatwe panguva imwe chete, inofambisa zvidzidzo zvakafanana uye kuedza.

Zvakanakira kushandisa zvakadzika mahwendefa

Uchishandisa zvakadzika mahwendefa anopa zvinoverengeka zvinowedzera zvinobudirira uye kurongeka mune yako laboratori:

1. Kuwedzera kugona.
2. Deredza njodzi yekusvibiswa: Iyo dhizaini yakadzika-yakadzika ndege inoderedza njodzi yekuyambuka pakati pemasampula uye inovimbisa kutendeka kwemhedzisiro yemhedzisiro.
3. Kuenderana ne automation.
4. Zvishandiso zvinochinja.
5. Mutengo-unoshanda.

mumhedziso

Mukupedzisa,Pakaderera mahwendefachikamu chakakosha cheMazuva ano Laboratory maitiro. Yavo inosiyana-siyana, yakawedzera simba, uye kuwirirana ne automation kunovaita chishandiso chakakosha kune vanotsvaga muminda yakasiyana siyana. Sezvo tsvarakayesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesaesa resainzi inoenderera mberi, kukosha kwemapurisa akadzika anokura chete, achivhura nzira yetsva azvinowanikwa uye zvigadzirwa. Kunyangwe iwe uchibatanidzwa mukuwanikwa kwezvinodhaka, mimhanzi yemanyorero, kana chero chimwe chirango chesainzi, kuisa mari mumhando yepamusoro mahwendefa echokwadi kunogona kuwedzeredza kugona kwako kwekutsvagisa.