Nhau 01
Kutanga kuwonekwa kweH4N6 Subtype yeVaian Peppment Virus muMallard Ducks (Anas Platyrhynchos) muIsrael
Avhaii lublin, nikki shkoda, luba Simanov, Gigal farnoushi Bar-Galeni, Pauline l getz, Pauline l getz, Pauline L Kamati, Raauri Ck Book, akamhanya naNathan
PMID: 35687561; DOI: 10.1111 / TBED.14610
Avani Semvura yemusango flowt inoendesa AIV mupasi rose, kuongorora kuwanda kweAIV muAlivity kwakakosha kuKunzwisisa pathogen kutapurirana uye kufanotaura chirwere chokubuda mumhuka nevanhu. Muchidzidzo ichi, H4n6 Subtype AIV yaive ichiparadzaniswa kwenguva yekutanga kubva kune faecal samples yemusango gomba madhiri (anas plotyrhynchos) muIsrael. Phylogenet mhedzisiro yeHA uye maini maGenera anoratidza kuti iyi madhiri ane hukama zvakanyanya neEuropean neAsia isopes. Sezvo Israeri iri pamwe neyeMiddle arctic-African migratory nzira, inofungidzirwa kuti dambudziko raigona kuunzwa ne shiri dzinofamba. Nyanzvi dzePhylogenetic yeMukati maGomeni Iyi H4n6 Subtype yeAIV ine chiyero chepamusoro, chinogona kukanganisa nguruve dzine hutano uye dzinosunga nzvimbo dzevanhu, uye zvinogona kukonzera chirwere cheziso mune ramangwana.
Nhau 02
Overview of Avia Featenza muEU, Kurume-June 2022
European Chikafu Chengetedzo Chiremera, European Center yekudzivirira kwechirwere uye kutonga, European Union Referator yeAvian Foratenza
PMID: 35949938; PMCID: PMC9356771; DOI: 10.2903 / J.Efsa.2022.7415
Muna 2021-2022, Pathogenic Auian Featenza (HPai) ndiyo yaive chidimbu chakakomba muEurope, ne 2,398 kubuda kweshiri dzinoguma nemamiriyoni makumi matanhatu nemashanu. Pakati pa 16 Kurume na10 June 2022, nyika yakazara 28 EU / eea nyika neUK 1 182 Cards), mhuka dzesango) uye shiri dzesango) uye shiri dzine hutapwa (22 kesi). Munguva yekudzokorora, 86% yePoultry kubuda kwePoulty yaive nekuda kwekutapurirana kweHPAIV, neFrance Account Germany yaive nehuwandu hwepamusoro hwekubuda mushiri dzesango (158 kesi), ichiteverwa neNetherlands (98 kesi) neUK (48 kesi).
Migumisiro yekuongorora genetic inoratidza kuti HPAIV parizvino endemic muEurope kunyanya ndeye spectrum 2.3.4 b. Kubva pashumiro yekupedzisira, ina H5n6, maviri H9n2 uye maviri H3N8 hutachiona hwave kutaurwa muChina uye imwe H5n1 hutachiona hwakataurwa muUSA. Njodzi yekutapukirwa yakaongororwa seyakaderera kune huwandu hwevanhu uye yakaderera kusvika pakati pezvakaenzana neyekuganhurirwa zvinhu zvakajeka muEU / eea.
Nhau 03
MUDZIMAI ASATIDZA 127, 183 uye 212 pane HAGE Genekara
Antiguenicity, replication uye Pathogenicity of H9N2 Apian Fileshenza Virus
Menglu Fan,Bing liang,Yongzhen Zhao,Yaping zhang,Qingzheng liu,Mioa Tian,Yiqing Zheng,Huizhi xia,Yasuo Suzuki,Haulan chen,Jihui Ping
PMID: 34724348; DOI: 10.1111 / TBED.14363
Iyo H9N2 SUBTYPE yeVIRIAN PEVISI Virus (AIV) ndeimwe yematambudziko makuru anokanganisa hutano hweiri indasitiri yehuku. Muchidzidzo ichi, madhiri maviri eH9N2 Subtype AIV neAige kumashure asi akasiyana antigenicity, anonzi A / Jiangsu / 75) Sequence Ongororo yakaratidza kuti JS / 75 neJS / 76 zvakasiyana mumatatu amino acid zvasara (127, 183 na 212) of Hagegglutinin (ha) yeHagegglutinin (ha) yeHagegglutinin Kuti uongorore mutsauko wezvivakwa pakati peJS / 75 uye 66, nhandare dzegumi nenhanhatu, Data kubva kuKukutora kwehuku uye Hi bvunzo yakaratidza kuti R-76 / PR8 yakaratidza inonyanya kutaurwa antigenic kupukunyuka nekuda kweAkino acid kusuta 127 na 183 muHa gene. Zvimwezve zvidzidzo zvakasimbisa kuti Glycosylation pa127n Nzvimbo yakaitika muJS / 76 uye yayo mutanji. Receptor kusunga assays yakaratidza kuti ese mauto ehutachiona hwese, kunze kwe127n Glycosylation-asina kukwana mutant, akasungirirwa kune vanhu vanogamuchira vanogamuchira. Kukura Kinetics uye Mouse Arttays Atays airatidza kuti hutachiona hwe127n-glycosylated shoma mumasero eA549 uye aive mashoma pathogenic mumakonzo akaenzaniswa neutachiona hwemusango. Saka, Gulcylation uye Amino acid shanduro muHa Geneko anokonzera mutsauko wekuti muAntiguenicity uye Pathogenicity of the 2 H9n2 Starins.
Kwayaka: China mhuka hutano uye epidemiology centre
Kutumira Nguva: Oct-20-2022